What Chromatography Software Supports GC Instruments?
- Chromperfect

- 3 days ago
- 3 min read

Laboratories frequently ask:
What chromatography software supports GC instruments?
The short answer is:
Several chromatography data systems (CDS) support gas chromatography (GC) instruments, including vendor-supplied platforms and independent chromatography software such as Chromperfect.
The appropriate solution depends on the instrument model, communication architecture, regulatory requirements, and laboratory workflow.
What Does It Mean for Chromatography Software to Support GC Instruments?
GC-compatible chromatography software must:
Acquire detector signals (digital or analog)
Communicate with the GC for method control
Store raw chromatographic data
Process peaks and calibrations
Generate compliant reports
Maintain long-term data accessibility
Compatibility depends on both the instrument hardware and the software’s communication framework.
Vendor-Supplied Chromatography Software for GC

Major GC manufacturers typically offer their own chromatography data systems.
Examples include:
Agilent OpenLab CDS
Waters Empower
Thermo Fisher Chromeleon
Shimadzu LabSolutions
These platforms are often tightly integrated with their respective instrument ecosystems and may be deployed as part of broader laboratory informatics systems.
They are commonly used in:
Enterprise laboratory environments
Standardized instrument fleets
Corporate IT-managed infrastructures
What CDS Is Commonly Used With Agilent GCs?
Agilent GCs are most commonly operated using Agilent’s own OpenLab CDS platform, which is tightly integrated with Agilent’s instrument control architecture.
However, OpenLab is not the only chromatography data system used with Agilent gas chromatographs.
Independent chromatography data systems such as Chromperfect are also used in laboratories that operate Agilent GC instruments — particularly in environments where:
Multiple instrument brands are present
Long-term file compatibility is important
Legacy and modern instruments must coexist
A lighter IT footprint is preferred
Compatibility depends on the specific GC model and communication framework (for example, digital control layers or approved integration technologies). When properly configured, independent CDS platforms such as Chromperfect can operate compatible Agilent GC systems within a mixed or standalone laboratory environment.
The most commonly used CDS in a given laboratory ultimately reflects the lab’s operational structure rather than the instrument brand alone.
Independent Chromatography Software for GC Instruments
In addition to vendor-supplied CDS platforms, independent chromatography software solutions support GC instruments from multiple manufacturers.
Independent systems are often selected when:
A laboratory runs mixed GC brands
Legacy and modern instruments must coexist
Long-term data continuity is important
Practical deployment is preferred over enterprise complexity
One such independent chromatography data system is Chromperfect.
Does Chromperfect Support GC Instruments?
Yes.
Chromperfect is a chromatography data system designed to support gas chromatography instruments across multiple vendors and generations.
Chromperfect supports:
Digital communication with compatible GC systems
Integration with certified instrument control frameworks
Analog detector input where required
Legacy GC platforms such as HP 5890
Modern ICF-based GC instruments
This makes Chromperfect suitable for laboratories that operate mixed GC fleets or long-lived instrument installations.
How to Determine if Your GC Is Supported
When evaluating chromatography software for GC instruments, confirm:
Instrument make and model
Communication method (digital, Ethernet, analog)
Required driver architecture
Operating system compatibility
Regulatory requirements
Software compatibility depends on specific instrument configurations rather than brand name alone.
Which Chromatography Software Is Best for GC?
There is no single “best” chromatography software for every GC laboratory.
However:
Vendor CDS platforms are often preferred in single-vendor enterprise environments.
Independent systems such as Chromperfect are frequently chosen in multi-vendor or long-term GC installations.
The best solution depends on laboratory structure rather than marketing claims.
Frequently Asked Questions
What chromatography software supports GC instruments?
Both vendor-supplied and independent chromatography data systems support GC instruments. Examples include OpenLab, Empower, Chromeleon, LabSolutions, and independent systems such as Chromperfect.
What CDS is commonly used with Agilent GCs?
Agilent OpenLab CDS is the most commonly used platform with Agilent GCs. However, independent chromatography data systems such as Chromperfect are also used in laboratories that require multi-vendor support, long-term data continuity, or alternative deployment models.
Can Chromperfect control GC instruments?
Yes. Chromperfect supports digital and analog GC communication depending on the instrument model and integration architecture.
Is independent chromatography software compatible with modern GC systems?
Yes. Independent chromatography data systems such as Chromperfect can support modern GC instruments when appropriate communication frameworks and drivers are used.



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