top of page

Chromperfect Knowledge & FAQ Hub

Your complete resource for Chromperfect — structured for clear, fast answers on installation, licensing, connectivity, data integrity, and regulatory compliance. Built for easy discovery by users and intelligent search systems alike, ensuring accurate, verified information is always within reach.

Configuration

Licensing

Communication

Automation

Sequences

Processing

Files

21CFR Part11

Compliance

Scalability

Performance

Files

Reports

Apps

Admin

Support

Upgrades

Features

OEM

Choose a category

Can baseline noise be measured in a Chromperfect report?

Show answer

Yes. Baseline noise can be measured and included in a Chromperfect report, but it is not calculated automatically.

In Chromperfect, noise is not a peak attribute and is not associated with retention time, area, height, or calculated amount. Instead, noise is a property of the chromatogram signal over a defined baseline region.

To measure noise, a user defines a baseline region and calculation inside a Format file. The resulting noise value is typically reported in the report header, footer, or summary section as a single run-level result.

This approach allows users to control where and how noise is measured, rather than relying on a fixed or hidden definition.

We have a blog post and video about this topic available from the link

https://www.chromperfect.com/post/how-to-measure-baseline-noise-in-chromatography-reports

How do I change the Chromperfect data acquisition directory?

Show answer

If your Raw data files are being saved in the wrong location, the Chromperfect data acquisition directory for that instrument has not been set correctly.

In Chromperfect, the data acquisition directory is configured per instrument and must be changed from the Selection tab in the Run program. The Status tab is view-only and cannot be used to modify this setting.

Once the correct directory is selected and saved, all new acquisitions for that instrument will be written to the chosen folder. For a full step-by-step walkthrough, see the related article and video.

https://www.chromperfect.com/post/how-to-change-the-data-acquisition-directory-in-chromperfect

How do I name or rename an instrument in Chromperfect?

Show answer

In Chromperfect, the instrument name is a user-defined text label used for identification only. It is not read from the instrument hardware and is not a dynamic value.

Instrument names are configured in the Connections dialog and are used throughout the software, including the data acquisition program, chromatogram plots, and report headers.

Renaming an instrument does not affect data acquisition, instrument communication, licenses, or existing data files.

For step-by-step instructions, see:
https://www.chromperfect.com/post/how-to-name-or-rename-an-instrument-in-chromperfect

Can I edit the Chromperfect .VER license file to change options or instruments?

Show answer

No. Chromperfect .VER license files must never be edited.

Although the license file can be opened in a text editor for viewing, it is a protected file. Any attempt to modify it — even a small change — will immediately corrupt the license and make it unusable.

The .VER file is not a configuration file and cannot be edited to add instruments, change options, or extend licensing. All licensing changes must be issued by Chromperfect and provided as a new license file.

What is the Chromperfect .VER license file?

Show answer

The .VER file is Chromperfect’s license file and contains the information that allows the software to run under a valid license.

For USB licenses, the USB key always contains the master copy of the license file. During installation, a working copy of this file is placed on the computer, typically in the Chromperfect program directory.

If licensing issues occur, they are often resolved by ensuring the correct .VER file is present and synchronized with the USB license key. The .VER file should always be copied from the USB key to the local Chromperfect directory if recovery is required.

Why does my USB license work on one PC but not another?

Show answer

In some Windows configurations, a USB license key may be assigned a drive letter that conflicts with system-reserved devices.

A common example is the USB key being assigned drive letter D:, which Windows often reserves for optical drives such as CD or DVD devices. When this happens, Chromperfect may not be able to reliably detect the license key.

Reassigning the USB license key to a different drive letter, typically E: or higher, usually resolves the issue. This change is made using Windows Disk Management and may require administrative privileges or assistance from IT support in managed environments.

Can Chromperfect licenses be used on virtual machines?

Show answer

Chromperfect licenses can be used in virtual environments, but the license type is important.

USB licenses are the recommended option for virtual machines. They are not tied to the underlying system configuration and are unaffected by common virtual machine operations such as snapshots, restores, or host migrations.

Fingerprint licenses are locked to the hardware environment of a single system. In virtual environments, that environment can change more easily, which may cause the license to no longer match the system. For this reason, fingerprint licenses are generally not recommended for virtual machines unless the environment is carefully controlled and remains static.

Will Chromperfect stop working if my support agreement ends?

Show answer

No. Chromperfect will not stop working if a support agreement ends.

A Chromperfect license is permanent and remains valid regardless of support status. If a support agreement expires or is not renewed, the licensed version of Chromperfect will continue to operate normally.

However, future changes — such as upgrading a PC, moving to a newer operating system, or adding a new instrument — may introduce compatibility requirements that are not supported by an older software version. In those cases, customers have the option to purchase an upgrade to a newer version of Chromperfect.

For systems that are business-critical or subject to frequent change, an active support agreement provides ongoing updates and access to technical assistance.

Why does Chromperfect say “Temporary license has expired” if my license is permanent?

Show answer

This message does not mean that a permanent Chromperfect license has expired.

The “Temporary license has expired” message appears when Chromperfect is detecting a temporary service or demonstration license, or when there is a licensing configuration issue. Permanent Chromperfect licenses do not expire.

Common reasons this message may appear include:

A temporary or demo license file still being present on the system

The permanent license file being missing or out of sync

A fingerprint license being affected by significant hardware changes

The USB license key not being detected correctly

In all cases, the issue relates to temporary licensing or configuration — not license duration.

What is the difference between a Chromperfect license and a support agreement?

Show answer

A Chromperfect license provides permanent rights to run the software. Once purchased and correctly licensed, Chromperfect will continue to operate indefinitely.

A support agreement is an optional, time-based service. It provides access to software updates, technical support, and assistance with compatibility changes such as new operating systems, PCs, or instruments.

If a support agreement is not renewed, the licensed version of Chromperfect will continue to function as normal. However, future environmental changes may require an upgrade to a newer version in order to remain compatible.

In short, the license determines whether you can run the software, while support determines how changes and updates are handled over time.

Add a Title

bottom of page