How detector noise biases baselines—and how to fix it with the right smoothing algorithm and window size in Chromperfect. Includes noise/RMS measurement, S/N, Savitzky–Golay derivatives, and when smoothing should (and shouldn’t) be used.

How Chromperfect’s timed events refine peak detection and baselines in tough chromatograms—covering CLAMP/FLIP, PW/TH/MUT, INT/HORZ/NEG, SBN/SBNV, SBAV/COM, and SKIM—plus when to use (and avoid) each.