Chromatographic data analysis is essential for turning raw HPLC and GC signals into accurate, meaningful results. From peak integration and baseline correction to calibration, system suitability, and compliant reporting, effective data analysis ensures reliability and confidence in every chromatographic run. This guide walks through the core principles, best practices, and the role of advanced software in delivering high-quality analytical data.

Start here if you’re new to Chromperfect. This Quick-Start video and guide walk you from installation to first results, including methods, calibration, reporting, and sequences.

See how Savitzky–Golay smoothing in Chromperfect v8.2.4 reduces high-frequency noise while preserving peak shape—plus derivative tools and practical tips from a long-time user.

Discover InterpretCannabinoids from Chromperfect — a turnkey data system for cannabis labs delivering fast, automated cannabinoid analysis, calibration, and reporting.

How digitization choices shape chromatography data: get sampling rate, range, resolution, and dynamic range right to preserve peak height, area, and retention time.

How detector noise biases baselines—and how to fix it with the right smoothing algorithm and window size in Chromperfect. Includes noise/RMS measurement, S/N, Savitzky–Golay derivatives, and when smoothing should (and shouldn’t) be used.

How Chromperfect’s timed events refine peak detection and baselines in tough chromatograms—covering CLAMP/FLIP, PW/TH/MUT, INT/HORZ/NEG, SBN/SBNV, SBAV/COM, and SKIM—plus when to use (and avoid) each.