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5.3 How to Automate Chromatography Workflows: A Guide to Chromperfect User Programs

  • Writer: Chromperfect
    Chromperfect
  • 12 minutes ago
  • 3 min read
This article provides an in-depth analysis of Chapter 5.3: User Programs and Automation from Section 5: System-Level Features and Automation of the Chromperfect Beginner Training Series.

The Chromperfect Beginner Training Series is organized into five core sections designed to take you from system foundations to advanced automation:


  1. System Foundations: Architecture, status indicators, and validation.

  2. Files and Method Fundamentals: Understanding methods, solutions, and data types.

  3. Working With Data: Navigation, integration, and calibration in the Analyze program.

  4. Reporting: Generating, customizing, and exporting results.

  5. System-Level Features and Automation: Sequences, security, and automated workflows.


This chapter addresses the common laboratory "pain point" of manual data handling. It explores how to transition from individual manual steps to a hands-free environment where external tools and background services handle the heavy lifting of processing and file management.


Chromperfect user programs and automation


While this guide covers the technical logic of automation, watching the video demonstration in our training playlist is essential to see exactly where these settings live within the Method File Editor and how the Sentry Service monitors your local network in real-time.


Key Takeaways: Chromperfect user programs and automation



  • User Programs allow external applications (like Excel or custom scripts) to trigger at specific workflow stages.

  • The Sentry Service provides "unattended" automation by monitoring directories for new data.

  • Automation is configured within the Method File, ensuring consistency across manual and automated runs.

  • There are three distinct trigger points for programs: Download-time, Process-time, and Alarm-time.


What Are Chromperfect User Programs?


Chromperfect is designed to be extensible, meaning it doesn't have to operate in a vacuum. User programs are the bridge between your chromatography data and the rest of your digital laboratory. These are external applications or scripts that Chromperfect "calls" or launches automatically.


Configured within the Method File Editor under the User Programs tab, these tools ensure that automation is a documented part of your analytical method rather than a separate, easily forgotten manual task.


The Three Types of User Program Triggers


Program Type

When It Executes

Common Use Case

Download-time

When settings are sent to the instrument.

Initializing external hardware or checking pre-run safety sensors.

Process-time

During automatic data file processing.

Exporting results to a LIMS, moving files to a server, or custom calculations.

Alarm-time

When specific reporting or alarm conditions are met.

Sending notifications or triggering emergency shut-off scripts if a result is out of spec.


How Does the Sentry Service Automate Workflows?


While User Programs handle specific actions, the Sentry Service handles the high-level workflow. Sentry operates as a background monitoring system that effectively "watches" designated folders for incoming data.


When a chromatography file is detected in a monitored directory, Sentry automatically:


  1. Assigns a predefined Method file.

  2. Applies analysis and integration settings.

  3. Generates the required reports or exports.


This is particularly powerful for integrated laboratory workflows where data might be generated by external systems or instruments running 24/7 without a dedicated operator present.


Pro-Tip: Methods Are Still the Boss


A common misconception is that automation replaces the need for careful method setup. In reality, the Sentry Service and User Programs rely entirely on your standard Method files.


Expert Insight: Always validate your method manually in the Analyze program first. Once the integration, calibration, and reporting are perfected in a manual workflow, the Sentry Service will replicate those exact results with 100% consistency in the background. If the method is flawed, the automation will simply produce flawed results faster.


People Also Ask


Where do I find the automation settings in Chromperfect?

User programs are configured directly in the Method File Editor under the "User Programs" tab. System-level automation like Sentry is managed as a background service.


Can Chromperfect launch Microsoft Excel automatically?

Yes. By setting Excel (or a specific macro-enabled workbook) as a Process-time user program, Chromperfect can launch the application and pass data to it immediately after a run is processed.


What is the difference between a Sequence and Sentry?

A Sequence (covered in Chapter 5.1) is a pre-planned list of injections managed by the user. Sentry is a "reactive" service that waits for data to appear in a folder, making it ideal for unattended or third-party data sources.


Does Sentry change how my data is integrated?

No. Sentry uses your existing Method files to perform processing. This ensures that whether a file is processed manually by a chemist or automatically by the service, the results remain consistent.

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