Chromperfect has evolved over decades to become a trusted chromatography data system used in laboratories worldwide. By combining simplicity, robustness, and strong regulatory features, it streamlines data acquisition, processing, and reporting for both GC and HPLC workflows. This post explores how Chromperfect’s long-standing design principles continue to enhance laboratory efficiency and reliability.

Chromperfect continues to support ProteinSimple iCE3 users with seamless Windows 11 compatibility, ensuring data integrity, validated workflows, and long-term continuity for legacy electrophoresis systems.

YouTube video which provides solutions for the Subscribe to data error for Agilent 7890 GCs If your Agilent 7890 Gas Chromatograph shows Ready in Chromperfect, you start a run, but no chromatogram appears — and after about a minute you see the error “Subscribe to Data” — this guide explains what’s happening and how to fix it. What Causes the Subscribe to data error Agilent 7890 GC Chromperfect This issue is not caused by Chromperfect. In fact, the software successfully sends

Start here if you’re new to Chromperfect. This Quick-Start video and guide walk you from installation to first results, including methods, calibration, reporting, and sequences.

Chromperfect Version 8.2 introduces barcode reporting — making data entry faster, more accurate, and free from human error. Learn how to embed barcodes into reports and streamline your chromatography workflows.

Learn how to fix the Chromperfect GetAcqServer Error that appears when starting data acquisition. Step-by-step instructions for restarting the CPAcqService in Windows.

See how Savitzky–Golay smoothing in Chromperfect v8.2.4 reduces high-frequency noise while preserving peak shape—plus derivative tools and practical tips from a long-time user.

Discover InterpretCannabinoids from Chromperfect — a turnkey data system for cannabis labs delivering fast, automated cannabinoid analysis, calibration, and reporting.

Introduction to chromatography peak theory: learn definitions of area, height, width, skew, tailing factor, kurtosis, resolution, and theoretical plates.

How digitization choices shape chromatography data: get sampling rate, range, resolution, and dynamic range right to preserve peak height, area, and retention time.

How detector noise biases baselines—and how to fix it with the right smoothing algorithm and window size in Chromperfect. Includes noise/RMS measurement, S/N, Savitzky–Golay derivatives, and when smoothing should (and shouldn’t) be used.

How Chromperfect’s timed events refine peak detection and baselines in tough chromatograms—covering CLAMP/FLIP, PW/TH/MUT, INT/HORZ/NEG, SBN/SBNV, SBAV/COM, and SKIM—plus when to use (and avoid) each.

Master chromatography calibration in Chromperfect: linear vs. non-linear fits, weighting for low levels, origin handling, precision metrics, troubleshooting, and internal standard strategies.

Learn why your changes may not appear saved in Chromperfect and discover the critical differences between RAW and bound (BND) files for chromatography data integrity.

Learn how to install Chromperfect with a fingerprint license, a virtual licensing option that replaces USB keys for secure and compliant software activation.

Experiencing Chromperfect license errors such as temporary license expired or license denied? Learn how to identify the problem using the built-in license information tool and resolve issues quickly with support or upgrade options.

The Chromperfect Main Menu serves as the central hub for launching programs, configuring access, and managing security. Learn how to use both the modern taskbar and the classic legacy menu.

Learn how to configure the Station Manager in Chromperfect, including logging, auditing, and instrument restrictions for local workstations.

Learn how to configure search directories, preferences, and printer settings with the Chromperfect Profile Editor. This guide ensures efficient chromatography workflows across multi-user and single-user environments.

Learn how to use the History Program in Chromperfect to view, filter, print, and archive data, error, alarm, and admin logs. Configure user/date filters, audit file activity, and generate targeted reports quickly.