Close-up of an HP 6890 gas chromatograph connected to a PC displaying an “Unexpected Reply / Error 104” communication message in chromatography software, with disconnected serial cables shown to illustrate troubleshooting a digital connection issue.

If the Chromperfect Run program crashes with an “Unhandled Exception” error when opening, the issue is usually due to a corrupted spreadsheet configuration file. Here’s how to fix it quickly.

Enable the operator field in Chromperfect to improve traceability and compliance. Step-by-step instructions for Version 6 and newer.